Thyroid Symptoms Are Not Caused by Your Thyroid Gland
Why are your thyroid numbers off in the first place? Without understanding and addressing the root cause of your thyroid symptoms, you’re likely to stay on thyroid medication for years, even decades (I’ve seen it happen!).
Being prescribed a thyroid medication doesn’t have to be a life sentence. This article will help you avoid that scenario and know which questions to ask at your next check-up.
Thyroid symptoms are not caused by the thyroid gland
I see you, dear reader…
You got your annual bloodwork results back from your doc. They say you’ve got high TSH and low T3, and that you need to be put on thyroid medication to fix it.
No one asked about your stress levels. No one questioned your energy, sleep, or diet. No one asked about your digestive health or work life.
You take the medication as instructed for several months, and your thyroid levels improve, but you still feel like garbage.
But, why?
Why are your thyroid numbers off in the first place? Without understanding and addressing the root cause of your thyroid symptoms, you’re likely to stay on thyroid medication for years, even decades (I’ve seen it happen!).
Being prescribed a thyroid medication doesn’t have to be a life sentence. This article will help you avoid that scenario and know which questions to ask at your next check-up.
Hi friends. I’m Hilary Beckwith, ex-dieter and holistic nutrition expert. Clients come to see me with signs of adrenal stress and inflammatory conditions, and my job is to find the root causes so we can address their symptoms more effectively, and fill in the gaps between what their doctor is saying and what their body is saying.
In this article, you’ll learn:
what thyroid symptoms can look like
how the thyroid gland works
what affects thyroid hormones throughout the body
what to ask for on your thyroid blood panels
thyroid symptoms
What do thyroid symptoms look like?
Throughout my life and career, I’ve learned something very important: Everything is a spectrum.
Thyroid symptoms don’t look the same for everyone, and this article should not be construed as a diagnosis or medical advice. If you think you have thyroid symptoms or other medical conditions, consult with a trusted physician or other qualified healthcare provider before making any changes. Read my medical disclaimer here.
**Much of the information in this article has been referenced from the Thyroid Debacle, although additional research has also been linked where applicable.**
HYPO-THYROID (slow or sluggish thyroid) SYMPTOMS CAN INCLUDE:
weight gain, difficulty losing weight
brain fog
poor circulation
constipation
depression
fatigue (frequently tired for no apparent reason)
dry skin
coarse hair
reduced libido (low sex drive)
HYPER-THYROID (overactive thyroid) SYMPTOMS CAN INCLUDE:
unexplained weight loss
irritability
anxiety
excess sweating or heat intolerance
nervousness
insomnia
increased appetite
increased heart rate
heart palpitations
tremors
fatigue
how the thyroid works
To understand the cause of your thyroid symptoms, we first need to understand what the thyroid is and does.
The thyroid gland is small and butterfly-shaped, and is located on the front (anterior) side of the neck. Its main function is to regulate cellular metabolism, which is the chemical processes cells undergo to create energy.
The thyroid gland acts in response to stimulation from the hypothalamus and pituitary gland, collectively known as the HPT axis.
Here’s a brief overview of how this works:
Hypothalamus (brain) senses the need for energy, releases TRH (Thyrotropin-Releasing Hormone)
TRH tells the Pituitary to release TSH (Thyroid Stimulating Hormone)
TSH stimulates the production of T4 (thyroxine, the inactive form of thyroid hormone) by the thyroid gland
Some T4 is converted to T3 (triiodothyronine, the active form of thyroid hormone) within the thyroid, but mostly this conversion happens within the tissues and cells where it is used
Most T3 and T4 are bound to a protein called thyroglobulin and circulate throughout the body until needed. Unbound, or free, T3 and T4 are able to bind to receptors and be used when needed.
T3 is required for many functions, but regarding your metabolism, it is required for the transport of glucose into a cell in order to make ATP (Adenosine TriPhosphate: the energy our cells use to function).
But it first has to be converted from T4, and avoid being converted to reverse T3 in cells (we’ll get to that).
3 things that affect thyroid hormones
#1 - high estrogen:
Tyrosine and iodine are two main components of thyroid hormones. Elevated estrogen stops iodine (iodide) from entering the thyroid gland.
Elevated estrogen increases circulating thyroxine-binding-globulin (TBG), decreasing the amount of FREE (usable) thyroid hormone in the body.
Elevated estrogen increases the activity of deiodinase 3, the enzyme responsible for deactivating thyroid hormone in cells in an effort to preserve energy. The hormone produced in this process is called reverse T3 (rT3).
#2 - high oxalates:
Oxalates, or oxalic acid, is found in many foods (including soy, leafy greens, rhubarb, parsley, and cassava), but is also produced by certain strains of fungus, including aspergillus, penicillium, and candida. Exposure to mold, mold toxicity, or candida overgrowth are common causes of high oxalates.
Oxalates have been found to cause tissue damage in the brain, nerves, kidneys, and thyroid gland, and elevations have been strongly correlated with autism cases.
When oxalates are elevated, they can bind to calcium to form oxalate crystals, which have a strong affinity for the kidneys and the thyroid gland. These crystals damage the gland tissues and interfere with their function. If you’ve ever had kidney stones, these are oxalic crystals.
#3 - prolonged chronic stress:
Any kind of stress activates your fight or flight system, which signals your adrenal glands to release cortisol in order to shift energy and blood flow to tissues and organs essential to fight or flight. Elevated cortisol levels signal the thyroid gland to produce more TSH (thyroid-stimulating hormone) and stop the conversion of T4 to T3.
This same stress response is modulated by the HPA axis (hypothalamus, pituitary, adrenal). Chronic stress means a chronic activation of the HPA axis, which interferes with the HPT[hyroid] axis we discussed earlier.
Unaddressed chronic stress causes cells to activate the Cell Danger Response (CDR) in order to preserve energy. CDR causes cells to stiffen cell walls to prevent nutrient transfer, release deiodinase 3 to deactivate thyroid hormone, and send out signaling hormones to summon immune cells to help. It’s your cells’ version of texting 9-1-1.
Examples of chronic stressors that often go unaddressed include:
what should be included in your thyroid labs?
When you have thyroid symptoms, testing for TSH and T4 are typically the only two things Western Medicine practitioners will test for. Occasionally, you might find a provider willing to also test for T3, free T4, and free T3.
Why so stingy with the testing? Because in the United States, most insurances require TSH to be elevated, and T4 to be low in order to diagnose hypothyroidism. Because these are the only two factors they require for diagnosis, insurance companies in the U.S. may not cover additional factors to be tested.
Being put on thyroid medication should not be a life sentence. Finding a practitioner who is willing to look for root causes of your thyroid symptoms is important. TSH and T4 are not enough to get a clear picture of the thyroid gland.
Here are some additional factors to request with your thyroid bloodwork:
TSH
T4, fT4
T3, fT3
rT3
thyroid antibodies
vitamin D (25OH and 1,25OH) - a high 125OH:25OH ratio suppresses thyroid antibody production. If this ratio is elevated, the thyroid antibody levels on your bloodwork may not be accurate.
estrogen (estradiol) - high estrogen affects thyroid function (as we discussed earlier). Estrogen levels are supposed to vary throughout your menstrual cycle. When testing for estrogen levels, it’s important to know which part of your cycle you’re in.
free iron (UIBC on labs) - elevated free iron levels may indicate increased cellular stress, and help you narrow the root causes of your thyroid symptoms.
CRP (C-Reactive Protein) - Elevated levels indicate increased inflammation, and may be indicative of cellular stress, pathogenic infection, or other internal stressors.
homocysteine - similar to CRP, elevated homocysteine may indicate increased inflammation due to tissue damage in the blood vessels. Elevated levels may also indicate a vitamin B12 and folate deficiency.
B12
folate
In addition to bloodwork, functional lab testing is essential to finding pathogenic infections that may be at the root of your thyroid symptoms.
I use functional lab testing to help my clients find parasites, overgrown bacteria, viruses, mold, and candida overgrowth. These are common pathogens that can contribute to cellular stress, inflammation, and thyroid symptoms.
Want to know more about how to support thyroid health? Read this article.
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